Excess Fat In Muscles Causes Diabetes 2 – Yes Fat!
People who have type 2 diabetes suffer from insulin resistance. Insulin resistance is the condition were the pancreas does not make enough insulin or the body cannot use insulin properly.
Insulin is needed to get sugar out of the bloodstream and into the cells for energy. The body converts sugar from foods into glucose and under normal conditions the pancreas will release enough insulin into the the bloodstream to get the glucose into muscle cells.
Insulin will then attach to receptors in muscle cells and this signals the cells to allow glucose to enter. Insulin is the key that unlocks the door and allows glucose to enter cells.
Excessive fat in the bloodstream builds up in muscles and creates toxic fatty byproducts and free radicals, and they block the insulin signaling process.  Insulin will knock on the door and try to get glucose in, but there won’t be anyone there to answer the door.
Glucose will then buildup in the bloodstream with no where to go, while the muscles crave for energy. The pancreas will increase insulin production to get the glucose out of the bloodstream, which only results in increased levels of glucose and insulin in the bloodstream.
This study was very eye opening as to whether fat or carbohydrate consumption played a greater role in developing insulin resistance. One group was fed a fat rich diet and the other group was fed a carbohydrate rich diet. Within two days the insulin resistance in the fat group skyrocketed and the group ended up with twice the blood sugar level than the carbohydrate group.
Another surprising fact is meat raises blood sugar levels as much as pure table sugar.
View the video for more details:
- M Krssak, K Falk Petersen, A Dresner, L Dipetro, S M Vogel, D L Rothman, M Roden, G I Shulman. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia. 1999 Jan;42(1):113-6.
- M Roden, T B Price, G Perseghin, K F Petersen, D L Rothman, G W Cline, G I Shulman. Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest. Jun 15, 1996; 97(12): 2859–2865.
- J Shirley Sweeney. Dietary Factors that Influence the Dextrose Tolerance Test a Preliminary Study. JAMA Int Med, Dec, 1927, Vol 40, No. 6.